Vector for the release of an active agent which is photocleavable by irradiation in the visible
Photocleavable molecules are of great interest as tools for diagnosis and various therapies thanks to the high spatiotemporal control over the release, but some issues preclude their clinical use. One open question is the frequency of the radiation required for the photocleaving process, which normally falls within the UV-violet region of the electromagnetic spectrum. These radiations are toxic to living cells and disadvantageous because of their short penetration depth into tissues. On the contrary, visible light and even the near infrared (NIR) result in reduced absorption and scattering, improving their penetration in tissues and reducing the toxicity. This invention relates to a new vector able to photo-release an active agent (such as a drug or a label) by visible or near infrared (NIR) triggering at low laser power.